
House holiday rentals in Panama City
Find and book unique houses on Airbnb
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 490 holiday rentals in Panama City

Verified guest reviews
Over 7,960 verified reviews to help you choose

Family-friendly holiday rentals
200 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 170 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
230 properties have a dedicated workspace

Wifi availability
460 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness and more.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Cozy cabin in nature with garden in Cerro Azul
Escape the city and enjoy a memorable stay in this charming cabin, just 50 minutes from Panama City, located within Chagres National Park. Surrounded by nature, it’s perfect for families or groups of friends. The cabin features 3 comfortable bedrooms, a fully equipped kitchen, WiFi, TV, and a beautiful garden. Enjoy nearby trails, rivers, and scenic viewpoints with the peace and security of a gated community. Perfect for relaxing, unwinding, and reconnecting with nature close to the city.

Large Private Residence in an Excellent Area
House in the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Kosher Option Available* House in one of the best areas of the country. Very quiet street, central, close to restaurants, pharmacies, mall, and more. Large, comfortable residence for groups.

House of the waterfalls
Your ideal escape: A hidden refuge in the Panamanian capital. Harmony between waterfalls and urban comfort. Rest in a natural environment, minutes away from everything. Wake up to birdsong and the relaxing sound of water. To make your stay more pleasant, we offer a swimming pool, pool table, board games, campfire area, spacious and equipped kitchen, three cozy rooms with private bathrooms. Enjoy a country experience to contemplate, share, or simply disconnect.

Spacious Family House Airport
Just 6 minutes from Tocumen International Airport, our comfortable house is an excellent option to rest and relax, a safe and quiet place, you have a 24-hour Supermarket with a Restaurant and Pharmacy 2 minutes away, 3 minutes from Tocumen Hospital and the Metro Station, 10 minutes from Los Pueblos Shopping Center and Metromall. In our house you can enjoy 3 bedrooms, 2 bathrooms, A/C, a large terrace, private parking, an equipped kitchen, Wi-Fi and Netflix.

Wonderful nature
Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the centre of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Its most outstanding features include a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

house-ac-wifi6-parking-family-car-hire
Welcome to our spacious and modern house for groups and families, with four bedrooms, each room has its own private bathroom and four full beds for a comfortable stay. With a large main kitchen and a small additional one in one of the bedrooms, you'll have everything you need to prepare your meals. Enjoy its spacious rooms, its exclusive car park and its location close to Costa del Este and the Panama Viejo ruins.

Comfortable and luxurious apartment
Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.
Popular amenities for house rentals in Panama City
House rentals with a pool

Capira Lidice 3 bedroom house bbq area

The Waterfall House

Casa Rouge by SS• Unique Stay w/ pool Near PTY

Villa la Vista - majestic mountain hideaway

Villa Monte María • Beautiful house in Cerro Azul

House with Private Pool and two parking spaces

Oceanfront views/access w/ Pool, Privacy & Space

Your country house, Menus de la Montaña, awaits you.
Weekly house rentals

Family-Friendly Panama Canal Home with Fenced Yard

Designer loft with private terrace

Cozy 1 bdr Apartment with A/C near Santa Maria

A little House in Panama City

Tiny House in the Nature by HYTTE HOMES

Swiss-Designed Cozy Home w/ Stunning Rooftop

Designer Canal Home - Med or Longterm

6A Golden Space | Design By Paradox
Private house rentals

Silence | Campfire | Garden | Pet-friendly

Country house in Altos de Cerro Azul

LovelyviewPty House 15 minutes away from the airport

Residence in Panama

Cabin in Cerro Azul with Forest View

Welcome to Zola Sierra! Your Escape Into Nature.

House in Altos de Cerro Azul. Pure nature.

Casa Radial
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