
House holiday rentals in Panama City
Find and book unique houses on Airbnb
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 480 holiday rentals in Panama City

Verified guest reviews
Over 8,400 verified reviews to help you choose

Family-friendly holiday rentals
200 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
240 properties have a dedicated workspace

Wifi availability
440 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness and more.

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.
4.9 out of 5 average rating, 118 reviews
Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well
4.97 out of 5 average rating, 94 reviews
Villa Flor house
Welcome to Casa Villa Flor — a comfortable and peaceful home located in the quiet San Antonio neighborhood. Conveniently located just 15 minutes from the airport, and within walking distance to MetroMall and the train station, making it easy to explore the area and travel around the city. Perfect for families or groups of up to 6 guests, the home includes: • Air conditioning • High-speed WiFi & Internet • Comfortable living spaces • Quiet residential atmosphere • No smoking
4.78 out of 5 average rating, 18 reviews
Large Private Residence in an Excellent Area
House in the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Kosher Option Available* House in one of the best areas of the country. Very quiet street, central, close to restaurants, pharmacies, mall, and more. Large, comfortable residence for groups.
4.75 out of 5 average rating, 125 reviews
Private Studio 10 Min from the Airport!
Spacious, newly renovated private apartment with a separate entrance, double bed, Wi-Fi, air conditioning, TV, fully equipped kitchen, hot water and everything you need for a comfortable stay. ❤️ Transport to and from the airport for an additional cost. Private Tours: - Panama Canal + Monkey Island and Emberá Community with lunch included. - Tours from Playa to San Blas. Early check-in 7am–2pm for $15, subject to availability. Stay, relax, and let us help you discover Panama! ✨
4.94 out of 5 average rating, 444 reviews
Central|Confort|surrounded by nature|Wifi|parking
Connect with the city and wonderful nature at the same time. Relaxing in a hammock on the balcony makes it unique. It will be great if you want to visit us for pleasure, work (high-speed WiFi); as a family or in groups of friends. House in the Old Canal Zone, Primer Alto; from here to explore tourist places and restaurants. (Near Bus Terminal, Metro Train, Albrook Mall, Metropolitan Park, Marcos Gelabert Airport, Old Town, Amador Coast Way, Canal de 🇵🇦)
4.84 out of 5 average rating, 118 reviews
Majestic Villa in the Mountains
Relax with the whole family at this peaceful place to stay. The majestic Villa Lola is a special place located in an exclusive residential area, with 24-hour security, Los Altos de Cerro Azul. A place within Chagres National Park surrounded by rivers, lakes, waterfalls, trails and endless wildlife species, where you can experience a different adventure every day. Located 55 minutes from the city and 30 minutes from Tocumen International Airport :)
4.94 out of 5 average rating, 80 reviews
Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.
4.84 out of 5 average rating, 128 reviews
Wonderful nature
Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!
4.82 out of 5 average rating, 57 reviews
Casa-confort-cercaacostadeleste-familia
Discover this elegant urban oasis, a completely refurbished retreat that combines comfort and style. The property has a large open-plan kitchen, three bedrooms ideal for seven people, including a king-size bed and a full-size bed, as well as two parking spaces. Enjoy relaxing afternoons on the outdoor terrace and take advantage of its unbeatable location just one block from Plaza de Santa María and two minutes from Costa del Este.
5.0 out of 5 average rating, 5 reviews
Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the centre of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Its most outstanding features include a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.
4.79 out of 5 average rating, 131 reviews
House for groups · 6 bedrooms/6 bathrooms near the Canal
Casa Randa is a fully equipped house ideal for families, friends and groups who value space and privacy. It has six rooms, each with a private bathroom, TV, minibar, air conditioning and ceiling fan. Enjoy a fully equipped kitchen, spacious social areas, Wi-Fi, a free washing machine and dryer, a BBQ, and private parking. Located in the quiet area of Diablo Heights, with easy access to the Panama Canal, Albrook and Gamboa.
4.89 out of 5 average rating, 18 reviewsPopular amenities for house rentals in Panama City
House rentals with a pool

House of the waterfalls
4.78 out of 5 average rating, 18 reviews
Oceanfront views/access w/ Pool, Privacy & Space
4.81 out of 5 average rating, 21 reviews
Your country house, Menus de la Montaña, awaits you.
4.77 out of 5 average rating, 30 reviews
La Fontana Scape
5.0 out of 5 average rating, 6 reviews
Carmen's House
5.0 out of 5 average rating, 14 reviews
Villa la Vista - majestic mountain hideaway
4.86 out of 5 average rating, 7 reviews
Oasis in Casco Viejo: Triplex, Rooftop, BBQ & Pool
4.57 out of 5 average rating, 7 reviews
Beautiful house in Brisas del Golf
4.89 out of 5 average rating, 9 reviewsWeekly house rentals

Apartment in Obarrio PB
4.83 out of 5 average rating, 82 reviews
Calm Oasis of Elegance & Nature.
4.95 out of 5 average rating, 19 reviews
Modern 3BR Mountain | Starlink WiFi | Cerro Azul
4.96 out of 5 average rating, 23 reviews
Welcome to Zola Sierra! Your Escape Into Nature.
4.96 out of 5 average rating, 25 reviews
A little House in Panama City
4.96 out of 5 average rating, 26 reviews
Cosy and Safe Environment Close to the Airport
5.0 out of 5 average rating, 22 reviews
Designer loft with private terrace
5.0 out of 5 average rating, 11 reviews
Cozy 1 bdr Apartment with A/C near Santa Maria
4.71 out of 5 average rating, 28 reviewsPrivate house rentals

Quiet Apartment Near Albrook and Ciudad Saber
4.66 out of 5 average rating, 35 reviews
Comfortable and luxurious apartment
4.89 out of 5 average rating, 35 reviews
Entire Home · Close to Irving Saladino Complex
4.77 out of 5 average rating, 22 reviews
Mountain paradise with peace and a cool climate
New place to stay
6A Golden Space | Design By Paradox
4.84 out of 5 average rating, 222 reviews
Unique 4 room house - direct access to the beach
4.85 out of 5 average rating, 103 reviews
CASA DE LINA HOSPITALITY, TRANQUILITY AND COMFORT
4.8 out of 5 average rating, 100 reviews
Tiny House in the Nature by HYTTE HOMES
4.81 out of 5 average rating, 47 reviewsDestinations to explore
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