
House holiday rentals in Panama City
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Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness and more.

On the beach, entire apartment, panoramic terrace and more
For those who love: Sea, Sun, Tropical, Tranquility, Freedom, Comfort. This exclusive apartment, directly on the beach, offers a unique view of the Gulf. Enjoy sunsets, sunrises, and walks. - On the large panoramic terrace, a sea-view bathtub. Sofa. Unique emotions. - 360° panoramic view with palm-leaf roof. - Queen bed, sofa, bathroom with shower, kitchen. * In the beachfront social area: - Hammock, barbecue, sofas, gazebo, kitchen, pool. Dcent of Paradise Pure Life Suitable for long stays.

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Apartamento Lilia Airport 1
"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

Designer Canal Home - Med or Longterm
Welcome to our little oasis in Panama City's historic Canal Zone! Our home has recently undergone a spectacular renovation with features that set it apart from other canal homes: luxury stone floors, tall ceilings, and an open, modern kitchen. It's the perfect retreat for someone who wants to be in the city but still surrounded by parks and wildlife. Note that we are ideally looking for guests who will stay for a month or more and would consider longer term tenancies if the fit were right.

Charming House in Casco Viejo
This recently renovated house is an absolute treasure. It blends history, charm, and modern comfort. Archeologists uncovered artifacts dating to the seventeenth century. Tastefully furnished with modern comforts and antiques, it's steps away from the Panama Canal Museum and in the heart of Casco Viejo, perfect for guests looking to immerse themselves in the cultural and culinary delights before retreating to the comfort and tranquility of their temporary home.

A Charming Colonial House in Casco Antiguo
Welcome to Casa Arango, a beautifully restored 19th-century gem in the heart of Casco Antiguo. Located on a quiet, picturesque street, this colonial house blends historic charm with modern comforts. Casa Arango offers three elegant rooms with private bathrooms, a front balcony, and a spacious patio with a barbecue and private bar. Perfect for families or groups of up to 8, the property also includes two private parking spaces—an exclusive luxury in the area.

Beautiful spacious full apartment near Albrook
Spacious and cozy apartment in a very quiet area surrounded by nature. The apartment is complete, everything is ready to welcome you. All services are included. Close to the Miraflores locks, Ciudad del Saber, the Metropolitan National Park, Cerro Ancón, and Albrook Terminal. Close to the Los Ríos pool. Accessibility for buses and taxis. For security reasons, cameras in the main entrance, terrace and patio. There are no cameras in indoor spaces.

Wonderful nature
Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Comfortable and luxurious apartment
Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.
Popular amenities for house rentals in Panama City
House rentals with a pool

Luxury Home with Pool in the Best Neighborhood

Luxurious beachfront home in Veracruz

A beautiful apartment with a swimming pool, BBQ area, and gym

Nice duplex house with a swimming pool.

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

Oceanfront views/access w/ Pool, Privacy & Space

House of the waterfalls

Airbnb - Vacation
Weekly house rentals

Modern house with a/c 10 mins from airport

Cozy house with a garden

2 bedroom apartment in the heart of Panama

Your Little House in Linda Vista

Casco Viejo 02, Luxury Condo, Panama Bay.

Cabin in Cerro Azul with Forest View

The Bird's Nest - Cerro Azul

Welcome to Zola Sierra! Your Escape Into Nature.
Private house rentals

House near the airport

Country house in Altos de Cerro Azul

Modern and minimalist Altos de Cerro Azul

Comfortable house in the nature of Panama Pacifico

House with Private Pool and two parking spaces

House with spectacular city and ocean views

LovelyviewPty House 15 minutes away from the airport

Altos de Cerro Azul Mountain House
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 470 holiday rentals in Panama City

Verified guest reviews
Over 7,710 verified reviews to help you choose

Family-friendly holiday rentals
180 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
230 properties have a dedicated workspace

Wifi availability
430 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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