
Holiday rentals in Panama City
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Top-rated holiday rentals in Panama City
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Yoo Panama, piso 54 cómodo y acogedor.
Hermoso departamento ubicado en el piso 54 del más lujoso edificio de Panama. Areas diseñadas por el Diseñador Philip Stark. Tiene 134 metros, está completamente amoblado, cuenta con un dormitorio, walking closet, un baño completo, sala comedor y cocina abiertos, medio baño social, terraza, cuarto de lavado. El edificio es un lugar único, con áreas comunales especiales y lujosas; 2 elegantes restaurantes; 2 piscinas; Gym; SPA; 2 canchas de squash; salsa de póker, lobby con mesa de billa, etc.

Elegant Apt - View to Main Plaza of Casco Viejo
Experience the charm of Casco Viejo with this beautiful apartment, located in the heart of the historic neighborhood - close to many dining options, cafes, supermarkets and attractions. Enjoy the stunning views of the Main Plaza from the comfort of your balcony or rest easy inside with the soundproof doors and strong WIFI connection. We provide a water biden throughout your stay for hydration and Panamanian coffee renowned as one of the best in the world, at the moment of check in.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

En el corazón de Casco, remodelado y con parking
Escápate y descubre casco antiguo en este remodelado , cómodo y céntrico alojamiento en el corazón de Casco Viejo. Nuestra ubicación es lo mejor, te hará regresar. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, cama king europea, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar -Cocina full equipada

Moderno y lujoso alojamiento en Cinta Costera
Vive la experiencia del lujoso PH Yoo con vista a la ciudad en este elegante apartamento con cama king y ventanales de piso a techo. Disfruta de amenidades de primer nivel: piscina, gimnasio, cancha de squash, spa y más. Ubicación privilegiada cerca de zonas turísticas, restaurantes, bares y centros comerciales. Dentro del edificio hay opciones gastronómicas con descuentos exclusivos y valet parking gratuito. Espacio moderno, amplio y sofisticado para una escapada inolvidable.

Beautiful apartment in Casco Viejo ST. George D
Bienvenido a nuestro espacioso y encantador apartamento en el Casco Viejo. Situado en un vibrante y histórico barrio. Te encantará la cálida atmósfera creada por las paredes de cal y canto, en perfecta armonía con nuestra moderna y elegante decoración. El espacio es grande y cómodo, ideal para relajarte después de un día explorando la ciudad. Como anfitrión, estoy disponible las 24/7 para responder a tus preguntas y asegurarme de que disfrutas al máximo de tu estancia.

Apartamento de lujo Panamá centro, área bancaria
Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

Apartamento completo en Panama
Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM
Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Superb Apartment In The Center Of Panama City
Luxurious, cozy, well-located 1-bed apartment in Panama City. Impeccably clean, stylishly furnished with a sofa bed. Experience the city's vibrant attractions, indulge in comfort, and make unforgettable memories. Your perfect getaway awaits! Book now for an exceptional stay.
Popular amenities for Panama City holiday rentals
Other great holiday rentals in Panama City

A Modern & Cozy Apartment In Prime Location

Elegante Apt en Costa del Este. Amenidades Premium

King Bed, Creative Design Steps from Casco Viejo

Elegant apartment with a view & the warmth of home

Amplío apartamento frente al Mar

Private parking & rooftop | Studio Casco Center

Luxury apt in Panama City 2 Rooms 3 Baths

Vista al Mar en la Avenida Balboa
Frequently Asked Questions
What are the best places to stay in Panama City?
Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.
What are the best things to do in Panama City with kids?
Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.
What are some of the best things to do in Panama City?
Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.
How is the weather in Panama City?
Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.
What are the best places to visit in Panama City?
Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.
What are some hiking trails in Panama City?
Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.
What are some family activities we can do in Panama City?
Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.
What are some of the best day trip ideas from Panama City?
Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.
Are there any pet friendly accommodations available in Panama City?
Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.
What are some local tips for visiting Panama City?
When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.
What is Panama City known for?
Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.
What are the best hidden gems to explore in Panama City?
Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.
What are the best foods to try in Panama City?
Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.
What should I bring for a trip to Panama City?
Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.
What is the nightlife in Panama City like?
Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.
What are the most popular events or festivals in Panama City?
Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.
Are there family friendly vacation rentals in Panama City?
Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.
When is the best time to visit Panama City?
The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.
Quick stats about holiday rentals in Panama City

Total holiday rentals
Explore 4,860 holiday rentals in Panama City

Verified guest reviews
Over 124,900 verified reviews to help you choose

Family-friendly holiday rentals
1,530 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,800 rentals that welcome pets

Holiday rentals with a pool
2,660 properties feature pools

Rentals with dedicated workspaces
2,930 properties have a dedicated workspace

Wifi availability
4,620 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Gym, BBQ grill and Laptop-friendly workspace across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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