House holiday rentals in Downtown Durham

A modern duplex with a welcoming front porch is showcased. The porch features wooden railings and potted plants on either side. A clear pathway leads to the entrance. The structure is set against a backdrop of trees and an expansive yard.

4.94 out of 5 average rating, 144 reviews

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

The exterior of the bungalow is presented, showcasing a well-maintained side with fresh white siding and a new roof. A welcoming red front door is highlighted, flanked by small shrubs and decorative landscaping. Tall trees are visible in the background, adding natural greenery.

4.95 out of 5 average rating, 176 reviews

Mirabelle- 3bd Downtown/Duke/RTP/No Cleaning Fees

Step into the comfort of this stylish, newly renovated 3- bedroom, 1- bath bungalow! CENTRALLY LOCATED & NEAR ALL MAJOR HIGHWAYS, Mirabelle is just minutes from downtown Durham, Duke University & RTP. No matter what brings you to Durham, Mirabelle has the perfect location & convenient amenities you’re looking for! * 5 min from downtown Durham * 10 min from Duke University & Duke Hospital * 10 min from RTP * 15 min from RDU airport * 10 min from Durham bulls and DPAC * 15 min from UNC hospital

A spacious living area features a sleek gas fireplace on one side, with modern artwork displayed on the walls. Comfortable seating includes a large gray sofa and green accent chairs, accompanied by a round coffee table. Natural light floods in through large windows.

4.95 out of 5 average rating, 105 reviews

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

4.98 out of 5 average rating, 261 reviews

A spacious living area is highlighted by a vibrant orange couch adorned with decorative pillows. Large windows fill the space with natural light, complemented by green plants that bring a touch of nature indoors. The open layout leads to a modern kitchen in the background.

Home in Hope Valley

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

4.91 out of 5 average rating, 476 reviews

A well-groomed dog stands on a wooden deck with a backdrop of lush greenery. Sunlight filters through the trees, creating a serene outdoor space. The deck features a blend of natural wood surfaces, complementing the relaxed atmosphere and inviting nature views.

Home in Forest Hills

The Bird's Nest

This newly renovated lower level apartment is nestled in the peaceful Forest Hills neighborhood. Our space is in an ideal location to enjoy all that Durham has to offer and comes complete with everything you'll need to feel at home. Minutes from excellent restaurants, outdoor fun, and cultural entertainment. Enjoy an evening at DPAC, a Durham Bulls baseball game, an energizing game of tennis at Forest Hills park, or a relaxing stroll through Duke Gardens. All just minutes from our doorstep.

4.98 out of 5 average rating, 122 reviews

A screened porch is illuminated by soft string lights, casting a warm glow against the exterior of the house. The porch features wooden furniture, and a well-maintained lawn is visible in the foreground. A tall tree provides shade beside the porch.

Home in Woodlake

Near Duke, Southpoint, UNC

Discover the perfect retreat in South Durham, NC! Our tranquil Airbnb offers an idyllic escape with a prime central location that guarantees a memorable stay. Start your morning on the inviting screen porch, where you can relish a cup of coffee and take in the view of the flower garden before headed out to enjoy some of the Triangle's finest attractions. Convenience is at your fingertips, as our Airbnb is just minutes away from RTP, RDU airport, Downtown Durham, DUKE, UNC, and the DPAC.

The kitchen area features white cabinetry and a wooden countertop. A modern fridge is positioned next to the entrance door, leading to a cozy living area with a brown sofa and a bright red chair. A colorful wall art piece adds a touch of decoration.

4.9 out of 5 average rating, 224 reviews

Clean Quiet Medical&Work Stay, Fenced Yard, Pets

Welcome to a spotlessly clean, quiet, and comfortable home in downtown Durham, thoughtfully set up for medical stays, longer work visits, and guests traveling with pets. Many guests choose this home while visiting Duke University Hospital, the VA Hospital, or Duke University, and appreciate having a calm place that feels easy to live in during what can be stressful or busy times. This is not a party house —it’s a peaceful, practical space designed to help you rest, reset, and settle in.

4.94 out of 5 average rating, 160 reviews

This historic home features a charming exterior with light green siding and a welcoming front porch. Surrounded by lush greenery and flower beds, the inviting walkway leads to the entrance, showcasing typical architectural details of the era.

Home in Downtown Durham

Rustic Historic Home~Short Walk to Downtown Durham

This historic home is only minutes from downtown Durham. It sits in one of the most beautiful neighborhoods in old Durham. It’s tree lined sidewalks can take you to parks, running paths and to one of the most vibrant downtowns in North Carolina . We are happy to offer you this 4 bedroom with 2 full bathrooms home with a well stocked kitchen with most everything you made need for making those epic dinners. Our large porch is a perfect place to hang out true to the southern style of leisure.

A single-story bungalow is displayed with a light blue front door. Symmetrical windows flank the door, and manicured shrubs are positioned on either side of the entrance. A concrete path leads up to the porch, enhancing the welcoming appearance.

4.99 out of 5 average rating, 199 reviews

Downtown Luxury/King Beds/ Walk Everywhere

Enjoy this luxury bungalow perfectly located in Downtown Durham. Walk to the best that Durham offers! Immaculately furnished throughout. King beds with two en suite full bathrooms. Wake up and walk to CocoCinnamon to enjoy a delicious morning cup of coffee. Later in the day, Motorco, Full Steam Brewery, The Farmers Market, Central Park, Saltbox Seafood Shack, and downtown restaurants galore await you to enjoy. DPAC and the Durham Bulls will be unforgettable nights out. Perfect location!

A cozy living area features a gray sofa paired with a wooden coffee table and a woven area rug. A comfortable chair is situated nearby, while a sleek floor lamp illuminates the space. A decorative fireplace with a chalkboard backdrop adds character to the room.

4.95 out of 5 average rating, 351 reviews

Reclaimed Beauty in Downtown's Cleveland-Holloway

Stay in a renovated, simplified Queen Anne-style home from 1915, located on the edge of Durham's Cleveland Holloway neighborhood with easy access to downtown's farmers market, restaurants, and bars. A portion of your stay goes to Airbnb.org to support hosting refugees. Relax in a spacious kitchen with Little Waves coffee, high ceilings, a beautiful live edge slab table, and a luxurious clawfoot tub shower. Please note, there is only one bathroom located in the master bedroom.

4.93 out of 5 average rating, 192 reviews

A charming blue cottage is shown with a front porch that features brick steps and a welcoming entrance. Lush greenery surrounds the home, with trees partially visible in the background under a clear blue sky.

Home in Walltown

Cozy home 2mi from DPAC & Duke Hospital!

Adorable dog friendly cottage in the heart of Walltown, one of the classic neighborhoods that drive Durham's popularity. One block from Duke East Campus, three blocks from the bars and cafes of 9th street, & a short Uber or Lyft to downtown or Duke hospital. The small cottage is full of charm and character with open kitchen and living area with granite counters, tiled kitchen and bath, and back screened porch. It offers Central heat and air, dishwasher, washer/dryer.

4.96 out of 5 average rating, 105 reviews

The modern kitchen features an expansive island with a white countertop and light wood cabinetry. Pendant lights hang above, while stainless steel appliances, including a double oven, are integrated into dark cabinetry. A living area is visible in the background, illuminated by natural light.

Home in East Durham

The Angier House | Modern Smart Home | 4Car Garage

Urban-modern near downtown living. Newly built and furnished 4 bedroom, 3.5 bath and features 2 owner suites, on first level and second level of the home. The house has a strong presence with minimal styling to create for a nice vibe and good times. Meticulous attention to detail everywhere you look from the chef-inspired kitchen to the two spacious en suite bathrooms.

Popular amenities for house rentals in Downtown Durham

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

A welcoming living area features a comfortable sectional sofa and two armchairs, arranged on a light area rug. A wooden coffee table occupies the center, adorned with decorative elements. Natural light filters through nearby windows, enhancing the open and airy layout.

4.99 out of 5 average rating, 68 reviews

1 story Ranch in South Durham/RTP/UNC/Duke/ RDU

4.94 out of 5 average rating, 16 reviews

The exterior of the home features a vibrant blue facade complemented by wooden accents. A spacious front porch is supported by two columns, providing sheltered entry. The yard includes a manicured lawn with small plants and a paved walkway leading to the entrance.

Home in Lyon Park

Stylish Downtown Durham Home

4.79 out of 5 average rating, 125 reviews

The front of the home features a charming exterior with blue shutters and a welcoming entrance. Lush purple flowers bloom vibrantly in the landscaped yard, complemented by green shrubs and a small tree. A driveway is visible, leading to the side of the house.

Home in Woodlake

3bd Lake pool access near Duke UNC Southpoint

5 out of 5 average rating, 5 reviews

Lovely home in Durham with Game/Movie Room!

A modern two-story home is presented with a light exterior, featuring a front porch and a driveway leading to a garage. The surrounding landscape includes a grassy area and trees in the background under a blue sky with fluffy clouds.

4.65 out of 5 average rating, 37 reviews

New Modern Home in the heart of Downtown Durham

4.92 out of 5 average rating, 38 reviews

The living room features a spacious sectional sofa arranged around a decorative coffee table. The soft carpet complements the wood flooring. A ceiling fan provides air circulation, and natural light fills the space from nearby windows. A staircase leads to the upper level, enhancing the open layout.

Home in Raleigh

RD Central: Modern Brier Creek home near airport

4.89 out of 5 average rating, 28 reviews

Guest house With Private Gate Near downtown

5 out of 5 average rating, 18 reviews

Home in Carrboro

Stylish Carrboro Townhome | Walk to UNC | Patio

Weekly house rentals

4.87 out of 5 average rating, 30 reviews

Home in West End

Cozy Durham Getaway near Downtown

5 out of 5 average rating, 68 reviews

A cozy living area is presented, featuring a coral-colored sofa with decorative pillows and a round glass coffee table. Natural light filters through two windows adorned with light curtains, highlighting a vibrant piece of artwork on the wall. A potted plant adds a touch of greenery.

Home in Walltown

Cozy Cottage with Fenced Yard

4.7 out of 5 average rating, 27 reviews

An open plan living space features a cozy sectional sofa with contrasting cushions, a round coffee table, and a dining area with a wooden table and six chairs. The kitchen is equipped with stainless-steel appliances and ample counter space. Natural light enters through the nearby window.

Home in Duke Park

Durham Cottage | 1 Mi to DT Durham

An open living area is featured, showcasing a neutral corduroy couch and two cozy armchairs. A wooden coffee table is center placed, and a welcoming entrance is visible. The space is illuminated by natural light, with access to a dining area and kitchen in the background.

4.96 out of 5 average rating, 46 reviews

Boho Downtown 5BD Home•BBQ•Mini Hot Tub•Pool Table

4.95 out of 5 average rating, 22 reviews

Boho Bungalow Retreat Minutes from Downtown

4.98 out of 5 average rating, 49 reviews

Modern Durham Retreat | Near Duke & Downtown

The living area features a combination of modern furniture, including a green sofa, orange chairs, and a round patterned ottoman. A central coffee table sits atop a black and cream geometric rug, while natural light streams in through multiple windows, illuminating the warm color palette.

4.97 out of 5 average rating, 68 reviews

Modern - Downtown, RTP, RDU, Duke, DPAC, Hospitals

4.88 out of 5 average rating, 49 reviews

The living area features a plush sectional sofa arranged around a 65-inch smart TV. An electric fireplace adds a cozy touch, while a stylish dining area is seen nearby, perfect for meals or gatherings. Bright decor and natural light enhance the welcoming ambiance.

Home in East Durham

3BR | Fenced Yard |Dogs OK| Near Duke U & Downtown

Private house rentals

5 out of 5 average rating, 9 reviews

Home in East Durham

Modern Stay Near Duke | Ideal for Travel Pros

A two-story home features a welcoming entrance with decorative stone pathways and lush green landscaping. A central staircase leads to the front door, framed by large windows. The surrounding trees provide a natural backdrop, enhancing the home's inviting curb appeal.

4.97 out of 5 average rating, 63 reviews

Entire home in RTP near Duke, fenced backyard

4.92 out of 5 average rating, 12 reviews

Cozy 3BD w/ Air Hockey, BBQ | Near Duke University

5 out of 5 average rating, 5 reviews

Spacious Retreat Near Duke | Fast WiFi + Parking

Home in Tuscaloosa-Lakewood

The exterior of a charming house is framed by tall trees, showcasing a well-maintained lawn and a gravel driveway. A vibrant yellow door serves as a focal point, complemented by white shutters and a cozy porch. The property is bordered by a privacy fence, providing a serene environment.

5 out of 5 average rating, 38 reviews

The Littlest House near Duke & Downtown Durham

4.98 out of 5 average rating, 41 reviews

A modern kitchen is presented with stainless steel appliances and ample cabinetry. A dining table features soft grey chairs and a potted orchid. To the left, a laundry area can be seen, while shelves display dishware and decorative pieces in the background.

Home in Duke Park

Charming Retreat Near Downtown Durham

5 out of 5 average rating, 13 reviews

Modern Private Cottage Near Duke & Downtown Durham

The charming two-story home features a covered front porch with white railings and comfortable seating. Well-maintained landscaping with colorful shrubs and flowers surrounds the concrete pathway leading to the entrance, creating a welcoming atmosphere.