
Hotel holiday rentals in Panama City
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Panama City
Guests agree: these hotel rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for hotel rentals in Panama City
Family-friendly hotel rentals

Beautiful B&B with unbeatable customer care!!!
The beach is very close by walking, but in the heat it is difficult to walk long distances. It is considerable to rent a cart early to ensure availability

Hostel Wunderbar Atlantis Room
Hostal Wünderbar is the ideal youth hostel, providing everything young adult travelers need and nothing they don't need. The manager, Richard, is an encyclopedia of local knowledge. The site endeavours to recycle food waste, which is another plus. I look forward to coming back one day!

Tanti 2, room in house on beachfront terrain
I highly recommend you to spend your vacation there. Francisco is an extraordinary welcome! We have dinner with him and his family. People with a big heart!! The beach and on-site facilities are worth a visit. The only negative point ( said with lots of love ) is that when booking we can't choose the room and the number of people. I could just book for one person. I was told that there would be an extra charge for the 2nd person. (my friend) At the end of my stay, I was charged double the price. I admit to being surprised and paying 2 x the price to be 2 in the room instead of one person. I may have had to inquire about the extra price when booking because it changes a hotel room budget… All of you, Francisco, and the people who work for him, of exceptional kindness:)

Eco Lodge Garden Room 4, Oceanview Plunge Pool
way better than described. authentic island feel, covered hammock area, literally against the jungle.beautiful

Pink Palace Panama
Great experience at Peggy's place, a top-notch hostess! Sweet, attentive and very helpful. Important that they know that they have 3 dogs, they are very friendly. The house is facing the sea, just steps walking to the shore.

Private Room #4. 3 people
Comfortable place and quite focused for backpackers. The photographs match the place. A good price.

Casa Momote Loma Limon
A hidden gem between trees and affection We had an unforgettable weekend in this corner of peace in Panama. From the first moment, Fernando and Mariel welcomed us as if we were old friends. Their warmth, their life stories, and the love with which they have built this space are felt in every corner of the place. The nearby river, the song of the birds and the tranquility of the environment make this place a true refuge from the daily noise. But what really makes this experience special is the energy that they have sown over the years: a mixture of hospitality, simplicity and soul. More than a home, it's a human experience. We were recharged, smiling, and full heart. Thank you so much Fernando and Mariel. This will not be our last meeting.

double room, island counter
We enjoyed our stay. The staff is always welcoming and super friendly. The service and the Food is delicious. We have stayed at Geralds mutiple times and we always enjoy it!
Hotel rentals with a pool

Your second home in Panama.
The truth is that I really liked it, I recommend it and I would return the clean facilities have the option of restaurants nearby, pool, the quiet area at night you can rest well, the only thing that gave the client the option to put if they want or not the daily cleaning in the room, otherwise all excellent.

Double room in Cosy pool hotel near Veracruz beach
The hotel facilities are very well, renovated and cared for and clean. Very friendly with the animals, we are very grateful for that.

Jr. Suite Rm #3- Cerro Azul
It was a great visit. I like how pet friendly La Semilla Ecolodge is. I hope the staff also were happy for hosting my mom, my pets, and me. It was a very relaxing experience and we loved the food! - The cook is one of the reasons I always come back :)

Rainforest Suite with Breakfast! 15 min from city
peacefully and beautiful place...

Double Suite-Apartment Hotel Príncipe
Super attention and check-in

In the heart of the city.
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!

Hotel Room with one full bed
Excellent
Hotel rentals with a patio

Nice hostel, ideal for family trips.
Helped us in need of a place to stay very quick and in national holiday

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.
Awesome place in a very nice neighbourhood. One of the most spacious rooms I had so far with a private bathroom and a fridge. Shared kitchen has everything you need and grocery stores and restaurants at walking distance. Friendly staff, fast and stable internet. Highly recommended great value for your money.

Eshel Panama Suites, Atlantic suite 04
Great host, beautiful place, great location! Enjoyed the stay!

Hotel Standard Room (2 Double Beds)
excelente lugar super recomendado

cinta costera
Great location and helpful staff

Grand Internationa Hotel - King Room
Excelente, we will return again.
Quick stats about hotel rentals in Panama City
Total rentals
120 properties
Nightly prices starting at
£8 before taxes and fees
Total number of reviews
2.8K reviews
Pet-friendly rentals
20 properties allow pets
Rentals with a pool
30 properties have a pool
Rentals with dedicated workspaces
90 properties have a dedicated workspace
Destinations to explore
- Playa Blanca Holiday rentals
- Ancón Holiday rentals
- Valle de Anton Holiday rentals
- Nueva Gorgona Holiday rentals
- Punta Chame Holiday rentals
- Rio Hato Holiday rentals
- Maria Chiquita Holiday rentals
- Contadora Island Holiday rentals
- Colón Holiday rentals
- Playa Santa Clara Holiday rentals
- Las Tablas Holiday rentals
- Cartagena Holiday rentals
- Rentals with a patio Panama City
- Beach apartment rentals Panama City
- Rentals with a firepit Panama City
- Serviced apartment rentals Panama City
- Flat rentals Panama City
- Beachfront rentals Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Fitness-friendly rentals Panama City
- Rentals with an EV charger Panama City
- Rentals with a washing machine and dryer Panama City
- Waterfront rentals Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Family-friendly rentals Panama City
- House rentals Panama City
- Pet-friendly rentals Panama City
- Rentals with beach access Panama City
- Rentals with outdoor seating Panama City
- Rentals with breakfast Panama City
- Hostel rentals Panama City
- Rentals with lake access Panama City
- Rentals with an accessible-height bed Panama City
- Smoking-friendly rentals Panama City
- Apartment rentals Panama City
- Rentals with a hot tub Panama City
- Villa rentals Panama City
- Rentals with a sauna Panama City
- Rentals with pools Panama City
- Rentals with a cinema Panama City
- Hotel rentals Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom