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Hotel holiday rentals in Panama

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Panama

Guests agree: these hotel rentals are highly rated for location, cleanliness and more.

Superhost
Boutique hotel in Bajo Boquete
Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix
15–22 AprIndividual Host,
£83 per night
4.92 out of 5 average rating, 106 reviews
Superhost
Boutique hotel in PA
Villa Coco King Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.
10–17 JulProfessional Host,
£137 per night
4.89 out of 5 average rating, 28 reviews
Guest favourite
Casa particular in Lagartero
Private Villa with private pool, in Santa Catalina
A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.
13–20 OctIndividual Host,
£84 per night
5.0 out of 5 average rating, 8 reviews

Popular amenities for hotel rentals in Panama

Family-friendly hotel rentals

Guest favourite
Casa particular in Bocas del Toro
Urania House
24 Jun – 1 JulIndividual Host,
£72 per night
4.96 out of 5 average rating, 80 reviews
Nature lodge in Darién Province
No Chunga
19–26 MayIndividual Host,
£27 per night
4.67 out of 5 average rating, 18 reviews
Superhost
Nature lodge in Taboga Island
Eco Lodge Garden Room 4, Oceanview Plunge Pool
29 Sept – 6 OctProfessional Host,
£63 per night
4.68 out of 5 average rating, 41 reviews
Superhost
Nature lodge in Puerto Lindo
Hostel Wunderbar Palm Room
29 Jun – 6 JulIndividual Host,
£29 per night
4.53 out of 5 average rating, 64 reviews
Aparthotel in Alto Boquete
Cabañas Villa San Miguel #1/noquete
5–12 JulProfessional Host,
£63 per night
4.67 out of 5 average rating, 21 reviews
Nature lodge in Isla Bastimentos
Beach Bungalow on Bastimentos w/ Meals & Transport
20–27 SeptIndividual Host,
£146 per night
4.92 out of 5 average rating, 24 reviews
Boutique hotel in San Carlos
B) Beach, surf and Relax with King size bed
24 Apr – 1 MayIndividual Host,
£55 per night
4.84 out of 5 average rating, 85 reviews
Guest favourite
Boutique hotel in Copecito
B&B Cabanas los hummingbirds
22–29 MayIndividual Host,
£78 per night
4.79 out of 5 average rating, 29 reviews
Nature lodge in Santa Catalina
Beachfront - Private double bedroom
13–20 DecIndividual Host,
£48 per night
4.8 out of 5 average rating, 15 reviews
Boutique hotel in Playa Venao
Marea - Ocean View Room with King Sized Bed
3–10 MarProfessional Host,
£138 per night
4.86 out of 5 average rating, 7 reviews
Boutique hotel in Playa Morillo, Mariato
Double room IXORA with partial ocean view balcony
21–28 JanIndividual Host,
£87 per night
4.97 out of 5 average rating, 33 reviews
Nature lodge in PA
VillaHermosa B&B
6–13 MarIndividual Host,
£156 per night
5.0 out of 5 average rating, 5 reviews

Hotel rentals with a pool

Guest favourite
Room in Panamá
Relax Room
14–21 AugIndividual Host,
£24 per night
4.81 out of 5 average rating, 16 reviews
Guest favourite
Hotel in La Enea
Private apartment with pool/beach access!
2–9 NovIndividual Host,
£42 per night
5.0 out of 5 average rating, 6 reviews
Guest favourite
Boutique hotel in Las Tablas Abajo
Blue Room for 2 - right on the beach!
29 Jul – 5 AugIndividual Host,
£48 per night
4.81 out of 5 average rating, 59 reviews
Guest favourite
Hotel room in Colón Island
Deluxe Oceanfront Bungalow - Bird Island Bungalow
25 Aug – 1 SeptIndividual Host,
£131 per night
5.0 out of 5 average rating, 19 reviews
Guest favourite
Boutique hotel in Lagartero
Charming 1-Bedroom Beachfront Hotel With Pool
10–17 MarProfessional Host,
£137 per night
5.0 out of 5 average rating, 8 reviews
Superhost
Boutique hotel in Panamá
Pool side, Family suite, two bedroom one bath.
28 Oct – 4 NovIndividual Host,
£62 per night
4.88 out of 5 average rating, 17 reviews
Superhost
Hotel in Playa Coronado
Your spot away from home
12–19 MarIndividual Host,
£93 per night
4.83 out of 5 average rating, 18 reviews
Guest favourite
Shared room in Panama City
Hostal Panama Experience
24–31 MarIndividual Host,
£10 per night
4.86 out of 5 average rating, 7 reviews
Superhost
Hotel in Panamá
Grand International Hotel
5–12 SeptProfessional Host,
£45 per night
4.75 out of 5 average rating, 4 reviews
Guest favourite
Nature lodge in Cacique
Isa’s jungle house, Roos
29 Jan – 5 FebIndividual Host,
£77 per night
5.0 out of 5 average rating, 5 reviews
Nature lodge in Bastimentos Island
Dolphin Serenity - Tropical Suite with Pool
4–11 JunProfessional Host,
£161 per night
5.0 out of 5 average rating, 4 reviews
Guest favourite
Resort in Cañas
Standard Suite
25 Aug – 1 SeptProfessional Host,
£143 per night
5.0 out of 5 average rating, 7 reviews

Hotel rentals with a patio

Superhost
Casa particular in Penonomé
Cozy 1 br 1 bath apartment with free parking
17–24 MarIndividual Host,
£48 per night
5.0 out of 5 average rating, 4 reviews
Casa particular in Río Hato
Villa in Playa Blanca Resort
13–20 MarIndividual Host,
£199 per night
4.5 out of 5 average rating, 4 reviews
Casa particular in Nueva Gorgona
Cabana Familiale au Panama
21–28 May
£55 per night
New place to stay
Casa particular in Bocas del Toro
Inchipinchi and Bochinche
17–24 OctIndividual Host,
£119 per night
New place to stay
Superhost
Nature lodge in Morrillo
Lovely Oceanfront Room in Adventure Lodge
31 Oct – 7 NovProfessional Host,
£69 per night
4.69 out of 5 average rating, 16 reviews
Superhost
Hotel in Bajo Boquete
Hobbit Home @ Bambuda Castle
11–18 JunProfessional Host,
£124 per night
4.64 out of 5 average rating, 11 reviews
Guest favourite
Room in San Miguelito
Travel break
31 Oct – 7 NovIndividual Host,
£23 per night
5.0 out of 5 average rating, 10 reviews
Guest favourite
Room in Soná District
SkyRoom- Private room with shared bathroom
27 Sept – 4 OctIndividual Host,
£59 per night
4.83 out of 5 average rating, 6 reviews
Hotel in Bocas del Toro
Seahorse A/C Mini Garden Cabin
15–22 MarProfessional Host,
£60 per night
4.59 out of 5 average rating, 39 reviews
Nature lodge in San Blas Islands
Natural rooms for disconnecting
4–11 DecProfessional Host,
£51 per night
5.0 out of 5 average rating, 5 reviews
Guest favourite
Hotel in El Valle de Antón
The King's Court
1–8 AprIndividual Host,
£77 per night
5.0 out of 5 average rating, 11 reviews
Hotel in Isla Grande
Paradise IslandBeach Hotel Double/Triple Room
20–27 MayIndividual Host,
£61 per night
4.62 out of 5 average rating, 26 reviews

Destinations to explore

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