
Pet-friendly holiday rentals in Panama City
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Panama City
Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

A cozy Casco Viejo apartment
Cozy 1-bedroom, 1-bathroom apartment in the heart of Casco Viejo! Fully equipped with a balcony, hot water, high-speed internet, air conditioning, Smart TV, work desk, and a complete kitchen with appliances. Perfect for remote work or exploring the historic neighborhood, with top restaurants, shops, and nightlife just steps away. Ideal for couples or solo travelers seeking comfort and convenience in a vibrant, iconic location. Relax, work, or explore—all from this charming retreat!

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Cozy 2 Bedroom w/ Splash Pool
Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Studio apartment in the heart of Casco
Welcome to Casa Pérez, your retreat in the heart of the Old Town! Enjoy a prime location and the best views from a spectacular private balcony facing the most iconic square in the Casco. Ideal for 3 people, this cozy and bright one-bedroom apartment includes Wi-Fi, air conditioning, living room, dining room, equipped kitchen, washing machine and elevator for your comfort. Enjoy an unforgettable stay in a warm and fully equipped atmosphere.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Amazing loft with Casco charm in the best location
Enjoy a stylish experience at this centrally-located loft-studio in the heart of Casco Viejo, the historic city of Panama. This chic apartment will give you all you need for your perfect vacation at the best location in Panama. Immerse yourself in the beautiful streets of this 350 years old city, get a taste of the local kitchen, enjoy a vibrant nightlife and experience the special vibe of Panama's most beautiful gems.

Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
Popular amenities for Panama City pet-friendly home rentals
Pet-friendly house rentals

Mountain Retreat

King Beds | 4BR | BBQ & Garden | pets ok!

Central|Confort|surrounded by nature|Wifi|parking

Villa Flor house

Spacious Family House Airport

Casa del Lago 2025

Majestic Villa in the Mountains

Spacious apartment-style house in El Dorado
Pet-friendly home rentals with a pool

Cozy apartment in Panama

Yoo Panama - Luxurious and comfortable

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Centrally located apartment.

Apartment Av. Balboa, Yoo&Arts

Modern and Cosy Apartment / The Gray

Luxury Oceanfront Resort 22nd Floor View, 200°

Centrally located condo for 4. Sea view
Private, pet-friendly home rentals

New studio apartment in front of the sea

Apartment near Tocumen Airport, Panama

Apt 2BR Panama Costa del Este

Modern Sky Studio with a View of the Panama Bay

Luxury apartment in the heart of Panama

Central Casco Escape with Charming Balcony

Panama Dream View Escape

Casco Viejo | Studio with Plaza Catedral View
Quick stats about holiday rentals that are pet-friendly in Panama City

Total holiday rentals
Explore 1,880 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at £7 per night before taxes and fees

Verified guest reviews
Over 58,630 verified reviews to help you choose

Family-friendly holiday rentals
710 properties offer extra space & child-friendly amenities

Holiday rentals with a pool
1,120 properties feature pools

Rentals with dedicated workspaces
1,320 properties have a dedicated workspace

Wifi availability
1,830 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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