
Mansion holiday rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.

BirdHouse@ Gamboa Panamá Canal
Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Spacious, Over the Water Home with Plunge Pool
Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Spacious 4Br Beachside Getaway at Playa Escondida
Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

OceanView-Rooftop Jacuzzi&Pool | Concierge Service
Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Private Pool/Buenaventura/Beach access/750MB
Spacious house located in Buenaventura. This high-end location features: - A Marina where you can load and unload your water toys! (at an extra cost) - Amazing restaurants where you can enjoy different flavors from around the world. - A fully stocked wine store where you will find a varied selection, as well as charcuterie and a excellent bread. - There are yoga and pilates classes - Social areas and beach access - A 19-hole golf course. - An amazing coffee store.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Tropical Haven with Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Spacious Vacation Home in a Tourist Area
Cozy & comfy villa with great illumination and natural ventilation located in the Playa Blanca Beach & Lagoon complex in Rio Hato, Cocle just 10 minutes away from Scarlett Martinez International Airport and 90 minutes from Panama City. Playa Blanca is an exclusive tourist residential beach complex with villas, apartments, big lush green areas, the largest pool in Central America, beach club, Playa Blanca Hotel Resort and much more.

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.
Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Spectacular Beachfront House
Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.

Modern | Steps to Beach Club & Shops | Sleeps 10
★ A Proper Rents Experience ★ • Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama

Unique Historic House in Casco
Hip five bedroom house in the heart of Casco Antiguo. Designed by world renowned restoration architect; this house is a perfect spot for exploring Panama's wonders. Ideal for families wanting to spend some time around the vibrant historic area.
Popular amenities for Panama mansion rentals
Luxury mansion rentals

Villa Solara 5 - Luxury 5 Bedroom Pool Villa

Stylish & Quiet ~ Breathtaking Laguna Views ~Pool

Hacienda La Perezosa in Cerro Azul

Villa Papagayo, Morrillo Beach, Veraguas

Beachfront Villa with Pool at the Heart of Venao

Opulent 4 bedroom Townhouse

Seahouse Bed & Breakfast Beach House with Pool

Villa Santorini | White Beach
Pet-friendly mansion rentals

Welcome to our house in Playa Corona

Private Beachfront Getaway

Laguna Fun and Sun: Your Escape Awaits

Between Multi Plaza and Omar Park

Charming house with beach access

Wonderful House with Terrace and Ocean View

Costa Blanca Beach & Golf Villa by Decameron

Exclusive apartment steps from the sea in Puntarena
Mansion rentals with a pool

Playa Escondida with sea and mountain views

Playa Escondida with the Best Direct Ocean View

Townhouse 256

Nice duplex house with a swimming pool.

Ocean, BBQ & marina - Playa Escondida Resort

Marina Condo W/Terrace & Patio

Buenaventura | Luxury Beach Apartment | Panama

Beach apartment in BUENAVENTURA
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