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Guest house holiday rentals in Panama
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Panama
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Panama
Family-friendly guest house rentals
![](https://a0.muscache.com/im/pictures/7f8ffa5b-deb5-401c-bc5c-cae41da2f0d4.jpg?im_w=720)
Guest house in Nueva Gorgona
4.99 out of 5 average rating, 67 reviewsBeautiful Casita-Paradise in Panama, Nueva Gorgona
![](https://a0.muscache.com/im/pictures/becfcffa-674e-4104-89cd-36cc53d95eec.jpg?im_w=720)
Guest house in Alto Boquete
4.82 out of 5 average rating, 65 reviewsAccommodation. Sinsonte )
![](https://a0.muscache.com/im/pictures/7370d2c1-692e-45a1-b26e-ab13d9d3f02d.jpg?im_w=720)
Guest house in Jaramillo Arriba
4.92 out of 5 average rating, 38 reviewsCaramel house
![](https://a0.muscache.com/im/pictures/bcfc9347-0528-4400-b1b0-c7c6a4c1904b.jpg?im_w=720)
Guest house in Bocas del Toro Province
5 out of 5 average rating, 4 reviewsLas Palmas Casita at Bluff Beach Retreat
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Guest house in Boquete
5 out of 5 average rating, 9 reviewsVista a Baru
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Guest house in Panamá
Mochila & Art Family House
![](https://a0.muscache.com/im/pictures/0b5865d8-1904-4025-872b-47a378524bb7.jpg?im_w=720)
Private room in Panamá
4.92 out of 5 average rating, 39 reviewsPrivate cabin and CasaMomote River, Loma Limón.
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Private room in PA
4.8 out of 5 average rating, 15 reviewsLa Rosa de Los Vientos, Pedasi, double room
Guest house rentals with a patio
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Guest house in El Valle de Antón
5 out of 5 average rating, 4 reviewsPrivate Suite/Studio 1-Bedroom in Paradise
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Guest house in Panamá
New place to stayMountainview Guest House @74
![](https://a0.muscache.com/im/pictures/hosting/Hosting-U3RheVN1cHBseUxpc3Rpbmc6MTA5NDM5NjM0MDE1MTE1NDI1NA%3D%3D/original/881dcdff-2461-4e52-a194-400f0bf1bcf5.jpeg?im_w=720)
Guest house in Nueva California
5 out of 5 average rating, 7 reviewsVolcano View Cottage
![](https://a0.muscache.com/im/pictures/4165b0f0-0d72-4410-99a2-acaacd26caca.jpg?im_w=720)
Guest house in Bocas del Toro
4.88 out of 5 average rating, 16 reviewsTiny Studio w/ pool access
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Guest house in Saboga
4.77 out of 5 average rating, 13 reviewsIsla Contadora - Beautiful 2 bedroom guesthouse
![](https://a0.muscache.com/im/pictures/miso/Hosting-911512295018542875/original/a2210ee5-2afe-428f-9a66-ff01d54fb173.jpeg?im_w=720)
Guest house in Boquete
5 out of 5 average rating, 4 reviewsCozy Garden Home W/Gazebo Overlooking Baru Volcano
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Guest house in San Félix District
5 out of 5 average rating, 3 reviewsPlaya Las Lajas Penthouse
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Guest house in Alto del Espino
5 out of 5 average rating, 3 reviewsTropical Suburban Splendor.
Guest house rentals with a washing machine and dryer
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Guest house in Panama City
4.81 out of 5 average rating, 73 reviewsEfficiency Bungalow - Metropolitan Natural Park
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Guest house in Nueva California
5 out of 5 average rating, 15 reviewsVolcan Cloud Forest Escape for two
![](https://a0.muscache.com/im/pictures/miso/Hosting-638989317155178210/original/dadb5433-bcdd-4274-b8e1-f9f8ae0d96c3.jpeg?im_w=720)
Guest house in Río Hato
4.88 out of 5 average rating, 65 reviewsSustainable Guest house with Pool in Rio Hato
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Guest house in Boquete District
5 out of 5 average rating, 9 reviewsDuplex 1
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Guest house in David
5 out of 5 average rating, 7 reviewsCozy, quiet and in an excellent location!
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Guest house in Los Naranjos
4.69 out of 5 average rating, 62 reviewsCabaas de Alicia 1
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Guest house in Boquete
4.67 out of 5 average rating, 9 reviewsCozy Studio Unit with Jawdropping Views!
![](https://a0.muscache.com/im/pictures/hosting/Hosting-1082586240835568666/original/36ebc1a5-985b-4862-b43f-9c8df2bb2abd.jpeg?im_w=720)
Guest house in La Concepción
New tropical guesthouse
Destinations to explore
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