Guest house holiday rentals in Panama
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Panama
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Panama
Family-friendly guest house rentals
Guest house in Alto Boquete
4.82 out of 5 average rating, 65 reviewsAccommodation. Sinsonte )
16–23 Feb
Guest house in Nueva Gorgona
4.99 out of 5 average rating, 67 reviewsBeautiful Casita-Paradise in Panama, Nueva Gorgona
19–26 Sept
Guest house in Bocas del Toro Province
5.0 out of 5 average rating, 4 reviewsLas Palmas Casita at Bluff Beach Retreat
14–21 Nov
Guest house in Jaramillo Arriba
4.92 out of 5 average rating, 37 reviewsCaramel house
14–21 Feb
Guest house in Boquete
5.0 out of 5 average rating, 9 reviewsVista a Baru
27 Nov – 4 Dec
Guest house in Chicá
Villa Altos de Campana, guess house for 6
1–8 Jul
Guest house in Panamá
Mochila & Art Family House
22–29 Dec
Guest house in Panamá
4.92 out of 5 average rating, 38 reviewsPrivate cabin and CasaMomote River, Loma Limón.
19–26 Jun
Guest house rentals with a patio
Guest house in Bajo Boquete
4.92 out of 5 average rating, 26 reviewsRustic Private Studio Near Downtown
25 Jun – 2 Jul
Guest house in Anton Valley
4.91 out of 5 average rating, 44 reviewsPrivate 1 BR cottage near India Dormida hiking
11–18 Sept
Guest house in Anton Valley
4.83 out of 5 average rating, 18 reviewsCabin The India
17–24 Aug
Guest house in Alto Boquete
4.82 out of 5 average rating, 17 reviewsBungalow Villa Castillo, Boquete.
11–18 Oct
Guest house in El Valle de Antón
5.0 out of 5 average rating, 4 reviewsPrivate Suite/Studio 1-Bedroom in Paradise
7–14 Aug
Guest house in Rio Sereno
5.0 out of 5 average rating, 3 reviewsThe Farmer’s Shack - Pure Nature
2–9 Nov
Guest house in Almirante
4.63 out of 5 average rating, 48 reviewsGia's Garage & Home for Bocas travelers
19–26 May
Guest house in Almirante
4.84 out of 5 average rating, 25 reviewsEntire guesthouse in Almirante, Bocas
12–19 Jun
Guest house rentals with a washing machine and dryer
Guest house in Alto Quiel
4.98 out of 5 average rating, 52 reviewsThe Casita at Finca Philadelphia
18–25 Jul
Guest house in Río Hato
4.88 out of 5 average rating, 60 reviewsSustainable Guest house with Pool in Rio Hato
9–16 Sept
Guest house in Boquete
4.67 out of 5 average rating, 9 reviewsCozy Studio Unit with Jawdropping Views!
24–31 May
Guest house in Boquete District
5.0 out of 5 average rating, 8 reviewsDuplex 1
20–27 Oct
Guest house in Cambutal
4.83 out of 5 average rating, 6 reviews"La Jungla" Cabaña close to the beach
17–24 May
Guest house in Los Naranjos
4.68 out of 5 average rating, 59 reviewsCabaas de Alicia 1
11–18 Feb
Guest house in Torio
4.8 out of 5 average rating, 5 reviewsCozy cabin w/ Queen Bed & ensuite mins from Beach
4–11 Jun
Guest house in San José
4.92 out of 5 average rating, 12 reviewsGuesthouse in Punta Barco Resort
3–10 Mar
Destinations to explore
- Cabin rentals Panama
- Rentals with beach access Panama
- Rentals with a firepit Panama
- Villa rentals Panama
- Rentals with a washing machine and dryer Panama
- Apartment rentals Panama
- Fitness-friendly rentals Panama
- Loft rentals Panama
- Pet-friendly rentals Panama
- House rentals Panama
- Hostel rentals Panama
- Rentals with an EV charger Panama
- Chalet rentals Panama
- Boutique hotel rentals Panama
- Family-friendly rentals Panama
- Rentals with breakfast Panama
- Treehouse rentals Panama
- Bed and breakfasts Panama
- Farm stay rentals Panama
- Hotel rentals Panama
- Smoking-friendly rentals Panama
- Rentals with lake access Panama
- Rentals with a patio Panama
- Boat rentals Panama
- Monthly Rentals Panama
- Rentals with pools Panama
- Nature eco lodge rentals Panama
- Beach apartment rentals Panama
- Mansion rentals Panama
- Island rentals Panama
- Rentals with a fireplace Panama
- Rentals with outdoor seating Panama
- Family-friendly rentals Panama
- Rentals with a cinema Panama
- Serviced apartment rentals Panama
- Beachfront rentals Panama
- Beach house rentals Panama
- Wheelchair-accessible rentals Panama
- Waterfront rentals Panama
- Flat rentals Panama
- Rentals with a kayak Panama
- Cottage rentals Panama
- Townhouse rentals Panama
- Tiny house rentals Panama
- Rentals with an accessible-height bed Panama
- Holiday home rentals Panama
- Rentals with a sauna Panama
- Rentals with a hot tub Panama
- Bungalow rentals Panama
- House rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom