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Boutique hotel holiday rentals in Panama

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Panama

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness and more.

Superhost
Boutique hotel in Bajo Boquete
Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix
15–22 AprIndividual Host,
£83 per night
4.92 out of 5 average rating, 106 reviews
Superhost
Boutique hotel in PA
Rancho Cabaña- Private Porch, Loft, 1 min to beach
No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.
13–20 JunIndividual Host,
£68 per night
4.84 out of 5 average rating, 43 reviews
Superhost
Boutique hotel in PA
Villa Coco King Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.
10–17 JulProfessional Host,
£137 per night
4.89 out of 5 average rating, 28 reviews

Popular amenities for boutique hotel rentals in Panama

Family-friendly boutique hotel rentals

Boutique hotel in San Carlos
B) Beach, surf and Relax with King size bed
24 Apr – 1 MayIndividual Host,
£55 per night
4.84 out of 5 average rating, 85 reviews
Guest favourite
Boutique hotel in Copecito
B&B Cabanas los hummingbirds
22–29 MayIndividual Host,
£78 per night
4.79 out of 5 average rating, 29 reviews
Boutique hotel in Playa Venao
Marea - Ocean View Room with King Sized Bed
3–10 MarProfessional Host,
£138 per night
4.86 out of 5 average rating, 7 reviews
Boutique hotel in Playa Morillo, Mariato
Double room IXORA with partial ocean view balcony
21–28 JanIndividual Host,
£87 per night
4.97 out of 5 average rating, 33 reviews
Guest favourite
Boutique hotel in Punta Chame
Pink Palace Panama
4–11 AugIndividual Host,
£85 per night
5.0 out of 5 average rating, 7 reviews
Boutique hotel in Boquete
Cabañas Villa San Miguel #5 / Boquete.
23–30 DecProfessional Host,
£63 per night
4.76 out of 5 average rating, 58 reviews
Hotel room in Puerto Armuelles
Beachfront Ocean Suite with Swiming Pool
7–14 MarIndividual Host,
£83 per night
4.53 out of 5 average rating, 19 reviews
Boutique hotel in isla contadora.
Beautiful B&B with unbeatable customer care!!!
8–15 SeptProfessional Host,
£145 per night
4.75 out of 5 average rating, 8 reviews
Boutique hotel in Portobelo
Beachfront Boutique Hotel and Restaurant Portobelo
30 Jul – 6 AugProfessional Host,
£90 per night
New place to stay
Superhost
Boutique hotel in Soná
Villa Coco Twin Room
10–17 MayProfessional Host,
£118 per night
5.0 out of 5 average rating, 4 reviews
Superhost
Boutique hotel in Soná
Villa Coco Jungle Villa
23–30 OctProfessional Host,
£223 per night
New place to stay
Boutique hotel in San Carlos
D) just a walk to the beach (Manglar Lodge)
12–19 JulIndividual Host,
£57 per night
4.8 out of 5 average rating, 56 reviews

Boutique hotel rentals with a patio

Boutique hotel in Bocas del Toro
Over the Sea Turtle Mini Cabin with Veranda
12–19 AprProfessional Host,
£87 per night
4.71 out of 5 average rating, 14 reviews
Boutique hotel in Pedasi
Room in Boutique Hostel; Private Bathroom
11–18 MarIndividual Host,
£44 per night
4.83 out of 5 average rating, 12 reviews
Boutique hotel in San Carlos
La Maracuyá Panama_ splendid large Room in Nature
19–26 JunIndividual Host,
£80 per night
5.0 out of 5 average rating, 3 reviews
Boutique hotel in Boca Chica
Tranquil Ocean View Cottage At Seagull Cove Resort
12–19 AprProfessional Host,
£161 per night
4.75 out of 5 average rating, 4 reviews
Boutique hotel in Soná District
Garden View Double Bedroom at Nativo
5–12 JulProfessional Host,
£72 per night
4.5 out of 5 average rating, 6 reviews
Boutique hotel in El Valle de Antón
Suite medievale natura & arte
6–13 MarIndividual Host,
£78 per night
4.38 out of 5 average rating, 8 reviews
Boutique hotel in Panamá
Eshel suites Panama , Kingston Suite 02
30 Jul – 6 AugIndividual Host,
£108 per night
New place to stay
Boutique hotel in Cambutal
Oceanfront Healing Sanctuary & Spa sunset
22–29 MarProfessional Host,
£129 per night
New place to stay
Boutique hotel in Panamá
Charming Hotel in Casco Viejo Santa Ana Deluxe
1–8 AprProfessional Host,
£209 per night
New place to stay
Boutique hotel in PA
Vida Lotus King Room with Hot Tub, Desk, and TV
30 Aug – 6 SeptIndividual Host,
£109 per night
New place to stay
Boutique hotel in Panamá
Beautiful Private Apartment in Old Town
6–13 MayProfessional Host,
£121 per night
New place to stay
Guest favourite
Boutique hotel in Bajo Boquete
The Residence - Colibri Room
25 Aug – 1 SeptIndividual Host,
£56 per night
5.0 out of 5 average rating, 16 reviews

Monthly boutique hotels rentals

Hotel room in Bajo Boquete
Buena Vista Boquete Quadruple Room
3–31 MayIndividual Host,
£761 per month
4.77 out of 5 average rating, 62 reviews
Boutique hotel in El Valle de Antón
HOSTAL EL MAJO DEL VALLE II
17 Jul – 14 AugIndividual Host,
£739 per month
4.56 out of 5 average rating, 93 reviews
Boutique hotel in Bocas del Toro
Private Double Room With Private Bathroom A/C WiFi
12 Nov – 10 DecProfessional Host,
£531 per month
4.19 out of 5 average rating, 16 reviews
Shared hotel room in Bocas del Toro
Selina Bocas del Toro - Bed in Small Dorm
28 Jul – 25 AugProfessional Host,
£744 per month
New place to stay
Boutique hotel in Panamá
Hotel san Roque
6 Mar – 3 AprProfessional Host,
£744 per month
New place to stay
Shared hotel room in Bastimentos Island
Selina Bocas del Toro Red Frog - Bed in Small Dorm
30 Jun – 28 JulProfessional Host,
£726 per month
New place to stay
Boutique hotel in David
Near bus station and downtown in David, Chiriqui
17 Feb – 17 MarProfessional Host,
£683 per month
New place to stay
Shared hotel room in Bocas del Toro
Selina Bocas del Toro - Bed in Large Dorm
6 Oct – 3 NovProfessional Host,
£635 per month
4.23 out of 5 average rating, 13 reviews

Destinations to explore