Some info has been automatically translated. Show original language

Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1
Top guest favourite
Flat in Panamá
4.93 out of 5 average rating, 138 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favourite
A historic building with a striking clock tower and decorative architecture is prominently featured in the image. Lush green trees surround the structure, and colorful rooftops of nearby buildings create a vibrant setting, emphasizing the area's cultural significance.
Flat in Panamá
4.89 out of 5 average rating, 201 reviews

Best Location – Spacious Luxury Apartment for 8

Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attractions

Top guest favourite
Flat in Panamá
4.97 out of 5 average rating, 118 reviews

Apt with unique views to remember

Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Top guest favourite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Flat in Panama City
4.96 out of 5 average rating, 108 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 184 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 149 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in Panama City
4.92 out of 5 average rating, 115 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of Casco Viejo, located on the third floor opposite one of Panama's most iconic squares, Plaza Catedral! Thanks to its privileged location, you'll enjoy a unique view of the square and the majestic Cathedral. Right in this lively square, you'll have a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Guest favourite
Flat in Panamá
4.9 out of 5 average rating, 111 reviews

Modern, central and comfortable (001)

Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!

Top guest favourite
Flat in Panama City
4.98 out of 5 average rating, 145 reviews

Exclusivo Ocean View 2BR/2BATH/Sky High & Rooftop.

Apartamento moderno de lujo en la Cinta Costera. Ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño espacioso, diseño elegante y electrodomésticos modernos. Amenidades: seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Cerca de supermercados y una gran oferta gastronómica. Ciudad de Panamá – Panamá.

Superhost
The studio apartment features a historic stone wall contrasted by modern furnishings, including a queen-size bed and sofa-bed. A dining table and working desk are present, with warm wood flooring enhancing the spacious feel. Natural light enters through large windows, illuminating the inviting space.
Flat in Panamá
4.91 out of 5 average rating, 412 reviews

3B Mola Studio | Design By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Guest favourite
A tree-lined street features a colorful pathway, with shaded seating areas and vibrant greenery along the sides. Cafés and restaurants are visible, providing a lively atmosphere. Cars are parked alongside the colorful path, leading into a bustling urban scene.
Flat
4.89 out of 5 average rating, 169 reviews

Lovely place in Via Argentina

Best neighborhood and street to stay in the city: El Cangrejo, Via Argentina. Close to public transportation, restaurants, cafes, parks and much more. My place is a comfy and clean place with a lot of amenities, you'll love it. If you have a question, please don't hesitate to ask.

Superhost
Flat in Marbella
4.81 out of 5 average rating, 126 reviews

Ocean Front Apartment, Best PTY Location

Beutiful apartment Ocean Front, 1 bedroom, 1.5 bathroom, 138sqm (1484sqf), fully furnished. Social area on the roof with gym,swimming pool, sauna. High speed internet, 2 Smart Tv, 70 inch and 50 inch. The apartment includ one parking space.

Popular amenities for Panama City apartment rentals

Quick stats about flat rentals in Panama City

  • Total holiday rentals

    Explore 2,860 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 88,500 verified reviews to help you choose

  • Family-friendly holiday rentals

    920 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,130 rentals that welcome pets

  • Holiday rentals with a pool

    1,940 properties feature pools

  • Rentals with dedicated workspaces

    1,910 properties have a dedicated workspace

  • Wifi availability

    2,790 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City
  5. Flat rentals