
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
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Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Best Location – Spacious Luxury Apartment for 8
Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attractions

Apto con vistas únicas para recordar
Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

YOO Eclectic & luxury seafront / 2BR / 45th floor
This unique place has a style all its own, superb seafront view with access to all main Panama City amenities, luxury fully furnished apartment on top notch building in Panama City. Apartments are a collaboration of Philippe Starck ideas, one of the world's most celebrated designers, and John Hitchcox, Manhattan Loft Corporation co- founder. Yoo Panama is in the heart of the Balboa Avenue, a spectacular strip bordering the ocean and offering magnificent views of the Panama Bay.

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

La mejor vista del Casco Antiguo
¡Bienvenidos a este encantador alojamiento situado en el corazón del Casco Viejo, ubicado en el tercer piso frente a una de las plazas más emblemáticas de Panamá, la Plaza Catedral! Gracias a su privilegiada ubicación, disfrutarás de una vista única a la plaza y a la imponente Iglesia Catedral. Justo en esta animada plaza, tendrás a tu disposición una amplia variedad de restaurantes y tiendas donde podrás adquirir recuerdos de este maravilloso viaje.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Apartamento completo en Panama
Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Suite Luxury 30th View Yoo Panamá & Arts Tower

Amaneceres únicos frente a la Bahía de Panamá

Cozy Casco Viejo Apartment

Casco Antiguo & Ocean View

Apartamento en el corazón de Casco Viejo Panama 15

2B • 5 Bedroom Apt • 4 Baths • Great for Groups

Cinta Costera Ocean View Suite

Luxury Oceanfront Resort 22nd Floor View, 200°
Private apartment rentals

VIP Suite/ Sea View + gym and Pool & Sky Lounge

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Lujoso apartamento en el corazón de Panamá

Unique Luxury 3-story Loft at the Yoo

Apartament w balcony in the heart of Panama City

Moderno apto en Obarrio • 1 cama +sofá cama

"Arrive as guests. Leave feeling at home".

Near Soho Mall •Urban Chic 1BR •Rooftop Pool/Views
Apartment rentals with a hot tub

Historic 2BR Loft at Casa del Horno, Casco Antiguo

Luxury 2BR Suite with Pool & Views

PH Yoo 44i – Apartamento con Vista al Mar

New Flat with Ocean + City Views

Apartamento Av. Balboa, Yoo&Arts

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Brand new apartment between rain forest and beach
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,860 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at £7 per night before taxes and fees

Verified guest reviews
Over 88,500 verified reviews to help you choose

Family-friendly holiday rentals
920 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,130 rentals that welcome pets

Holiday rentals with a pool
1,940 properties feature pools

Rentals with dedicated workspaces
1,910 properties have a dedicated workspace

Wifi availability
2,790 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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