
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
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Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Best Location – Spacious Luxury Apartment for 8
Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attractions

Apto con vistas únicas para recordar
Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Chic Studio in Casco Antiguo - View to Main Plaza
Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

La mejor vista del Casco Antiguo
¡Bienvenidos a este encantador alojamiento situado en el corazón del Casco Viejo, ubicado en el tercer piso frente a una de las plazas más emblemáticas de Panamá, la Plaza Catedral! Gracias a su privilegiada ubicación, disfrutarás de una vista única a la plaza y a la imponente Iglesia Catedral. Justo en esta animada plaza, tendrás a tu disposición una amplia variedad de restaurantes y tiendas donde podrás adquirir recuerdos de este maravilloso viaje.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Apartamento completo en Panama
Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Moderno, céntrico y cómodo (001)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama full, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad!

Exclusivo Ocean View 2BR/2BATH/Sky High & Rooftop.
Apartamento moderno de lujo en la Cinta Costera. Ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño espacioso, diseño elegante y electrodomésticos modernos. Amenidades: seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Cerca de supermercados y una gran oferta gastronómica. Ciudad de Panamá – Panamá.

Lovely place in Via Argentina
Best neighborhood and street to stay in the city: El Cangrejo, Via Argentina. Close to public transportation, restaurants, cafes, parks and much more. My place is a comfy and clean place with a lot of amenities, you'll love it. If you have a question, please don't hesitate to ask.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Unique Luxury 3-story Loft at the Yoo

Cinta Costera Ocean View Suite

Villas La Fontana Spacious ApartaSuite - Pool 102

Amazing experience in Casco Viejo historical site3

2-Bedroom Apt Ocean Views PH Yoo

"Arrive as guests. Leave feeling at home".

Oasis de lujo en el Casco Viejo de Panama

PH The Gray | Balcony Views · Pool · Gym
Private apartment rentals

Elegante Apt en Costa del Este. Amenidades Premium

Tu Hogar frente al Mar

Modern apartment in Obarrio with a true home feel

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Lujoso apartamento en el corazón de Panamá

61B Apto Moderno con Vistas al Océano de 1 hab

2B • 5 Bedroom Apt • 4 Baths • Great for Groups

Luxury Oceanfront Resort 22nd Floor View, 200°
Apartment rentals with a hot tub

Suite Luxury 30th View Yoo Panamá & Arts Tower

Historic 2BR Loft at Casa del Horno, Casco Antiguo

Luxury 2BR Suite with Pool & Views

New Flat with Ocean + City Views

Apartamento Av. Balboa, Yoo&Arts

Panama Dream View Escape

Apartment with the warmth of home and ocean view

Apartamento Lujoso en Marbella
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,860 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at £7 per night before taxes and fees

Verified guest reviews
Over 88,500 verified reviews to help you choose

Family-friendly holiday rentals
920 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,130 rentals that welcome pets

Holiday rentals with a pool
1,940 properties feature pools

Rentals with dedicated workspaces
1,910 properties have a dedicated workspace

Wifi availability
2,790 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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