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Apartment holiday rentals in Panama

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Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.93 out of 5 average rating, 138 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Superhost
A charming historic building features ornate white architecture with teal accents. Arched windows and balconies are visible on the upper levels, showcasing decorative wrought-iron railings. The entrance showcases double doors, inviting passersby to explore the structure's elegance.
Flat in Panamá
4.83 out of 5 average rating, 179 reviews

Best location - Unique and charming loft

Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Top guest favourite
Flat in Panamá
4.97 out of 5 average rating, 118 reviews

Apt with unique views to remember

Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Guest favourite
A cozy sleeping area features a spacious bed with a light-colored patterned coverlet. Two bedside tables with lamps are positioned on either side, and a decorative wooden tray with wine and glasses sits on the bed. Textured stone and brick walls provide a rustic backdrop.
Flat in Panamá
4.9 out of 5 average rating, 455 reviews

Chic Studio in Casco Antiguo - View to Main Plaza

Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Guest favourite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Flat in Juan Gallego
4.88 out of 5 average rating, 153 reviews

Pebos Reef Apt 2 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 184 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favourite
Flat in Panama City
4.97 out of 5 average rating, 115 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 149 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Flat in Panama City
4.92 out of 5 average rating, 115 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of Casco Viejo, located on the third floor opposite one of Panama's most iconic squares, Plaza Catedral! Thanks to its privileged location, you'll enjoy a unique view of the square and the majestic Cathedral. Right in this lively square, you'll have a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Guest favourite
Flat in Panamá
4.9 out of 5 average rating, 111 reviews

Modern, central and comfortable (001)

Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!

Top guest favourite
Flat in Panama City
4.96 out of 5 average rating, 161 reviews

LUXURY APT / Sea View & SKY Lounge.

Modern luxury apartment on the Cinta Costera, ideal for executives, couples or families. Large bedroom with ocean view, private bathroom, kitchen and appliances. Elegant design with 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Prime location near supermarkets and excellent cuisine in Panama City. PANAMA

Guest favourite
A spacious balcony is equipped with comfortable seating, offering views of the blue ocean and a partially visible pool area. Lush greenery surrounds the space, and a few palm trees sway gently in the breeze under a clear sky.
Flat in San Carlos
4.93 out of 5 average rating, 216 reviews

Punta Caelo Apartment

New, cozy and stylish 4 bedroom apartment, fully equipped in Punta Caelo. Just 70 minutes from Panama City, enjoy this great luxury residential complex, facing the Pacific Ocean.

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