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Apartment holiday rentals in Panama

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama

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Top guest favourite
A comfortable seating area features a wooden couch adorned with light-colored pillows. Large windows provide a view of the lush greenery outside, while a warm light fixture adds a soft glow to the room. The space is complemented by a simple wooden table and concrete flooring.
Flat in Provincia de Veraguas
4.94 out of 5 average rating, 125 reviews

Casa Melina Torio Cozy upscale 2b jungle apartment

Stylish jungle two bedroom apartment near all major Torio attractions: waterfall, jungle trails, Torio River, Playa Torio & Morrillo Surf break. The apartment is fully equipped with everything you need & want (Hot water, AC, WiFi & TV). Perfect for a couple/family seeking to blend work and play. Casa Melina was designed so our guests can fully experience our Torio culture. Cook with local fresh ingredients, discover Torio on foot & return to rest in the coziest rental you have ever experienced.

Guest favourite
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Flat in Panamá
4.87 out of 5 average rating, 375 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Flat in Panamá
5 out of 5 average rating, 61 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Guest favourite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Flat in Juan Gallego
4.87 out of 5 average rating, 147 reviews

Pebos Reef Apt 2 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favourite
An open living space features a large gray sectional sofa paired with a round wooden coffee table. A patterned rug lies beneath, complementing the light wooden flooring. The kitchen area is visible in the background, showcasing modern appliances and a breakfast bar with stools.
Flat in Panamá
4.94 out of 5 average rating, 170 reviews

Cozy 2 Bedroom w/ Splash Pool

Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Top guest favourite
A rooftop terrace features a wooden hot tub surrounded by potted plants and a stone pathway. In the background, historical ruins are visible, complementing the vibrant atmosphere of the area. Seating areas and greenery contribute to a relaxing outdoor space.
Flat in Panamá
4.94 out of 5 average rating, 102 reviews

Beautiful apartment in Casco Viejo ST. George D

Bienvenido a nuestro espacioso y encantador apartamento en el Casco Viejo. Situado en un vibrante y histórico barrio. Te encantará la cálida atmósfera creada por las paredes de cal y canto, en perfecta armonía con nuestra moderna y elegante decoración. El espacio es grande y cómodo, ideal para relajarte después de un día explorando la ciudad. Como anfitrión, estoy disponible las 24/7 para responder a tus preguntas y asegurarme de que disfrutas al máximo de tu estancia.

Superhost
A modern living area is featured with a neutral-toned sofa adorned with accent pillows. Natural light floods the space through large windows, showcasing views of the city. A circular coffee table sits in front of the sofa, complemented by a decorative plant and wall art.
Flat in Panamá
4.82 out of 5 average rating, 111 reviews

Modern Cozy Apartment · Pool, Gym & Coworking

Welcome to our charming apartment in the heart of Panama City! Perfect for digital nomads who take their office with them. At LIVING 73 you will enjoy a wide range of amenities, such as swimming pool, a coworking space and gym. Located in the San Francisco area, it's the perfect starting point for exploring the city. You will find within a 5 minute walk a wide range of restaurants, supermarkets and the Multiplaza Mall, the largest and most varied in the city.

Top guest favourite
Flat
4.97 out of 5 average rating, 34 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 170 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
A modern living space features a flat-screen TV mounted on a textured wall, paired with a stylish coffee table and a floor lamp. Soft natural light filters through sheer curtains, illuminating the adjacent bedroom, which contains a cozy bed and bedside tables.
Flat in Panamá
4.97 out of 5 average rating, 33 reviews

Beauty Balcony •Remote Working • Near Multiplaza

➤ Stylish and beautiful apartment, tailored for remote workers with balcony, minutes away from Multiplaza Mall . ★ Perfect for Remote Workers, desktop and 150 MB speed internet. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Shopping ➤ Urban Escape - Building Highlights: ★ Gym ★ 2 Co-Working Space with 500 MB speed internet ★ Pool on the Rooftop Terrace ➤ Located in San Francisco: Explore the City Easily | Uber-Friendly

Top guest favourite
Flat in Panama City
4.97 out of 5 average rating, 99 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 138 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

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